Buddy Guy (born George Guy, July 30, 1936 in Lettsworth, Louisiana) is an American blues music and rock music guitarist, as well as a singer. He learned guitar on a homemade instrument, influenced by both widely known and local blues guitarists. Known as an inspiration to Jimi Hendrix he is one of the greatest exponents of Chicago blues made famous by Muddy Waters and Howlin' Wolf. He is said to be a thrillingly inventive guitarist. For example, he plays with drumsticks and walks into the audience whilst playing, the latter is a gimmick he picked up from a local blues guitarist at an early age (joining or leaping into the audience has also long been common in both American popular and gospel music, as in the earlier work of Big Jay McNeely or the Dixie Hummingbirds). Eric Clapton once said of him, "By far and without doubt the greatest guitarist alive today".

Guy first recorded on bass guitar for legendary Chess Records before performing as a band leader. He also backed Chess recording artists on a black and white polka-dotted Fender Stratocaster, and claimed Phil and Leonard Chess would not allow him turn up the volume on his amp. He recorded on Junior Wells sessions for Delmark Records under the pseudonym Friendly Chap in 1965 and 1966. His career really took off during a blues revival period in the late 1980's and early 1990's.

Notable albums include Stone Crazy, Damn Right I've Got The Blues, Feels Like Rain, Blues Singer, Buddy's Baddest: The Best Of Buddy Guy, and Junior Wells' Hoodoo Man Blues.

His club, Buddy Guy's Legends (http://www.buddyguys.com/), is a popular club in Chicago.

In 2005, he will be inducted into the Rock and Roll Hall of Fame.