Margrethe of Savoy (Turin, November 20, 1851- Bordighera, 1926), was the Queen of Italy during the reign (1878-1900) of her husband, Humbert I.

She was the daughter of Ferdinand, Duke of Genoa and granddaughter of Carlo Alberto.

She married her cousin Humbert (Umberto) in 1868. On November 11 , 1869, Margherita gave birth to Victor Emmanuel, Prince of Naples, afterwards Victor Emmanuel III of Italy.

Namesake of Pizza Margherita, her name means "daisy" in Italian.

She encouraged artists and writers and founded cultural institutions, notably the Società del Quartetto, and the Casa di Dante. She benefited many charities, especially the Red Cross.